Estriol
Synonyms: oestriol; 1, 3, 5(10)-Estratriene-3, 16a, 17b-triol
CAS: 50-27-1
EINECS: 200-022-2
Assay: 97.0%-102.0%.
Packing: foil bag.
Delivery: Express courier.
Character: White crystalline powder.
Usage: A metabolite of Estradiol. An estrogenic metabolite considerably less potent than the hormone Estradiol. pharmaceutical material, Steroid hormone, estrogen.

Purpose and Function
1. It can be used for treating cervicitis and especially suitable for treating menopausal syndrome and senile vaginitis.
2. It can also be used as the adjuvant drug for middle-term labor induction and artificial abortion.
3. It can also be used for treating prostatic hypertrophy and prostate cancer.
4. It still has a rapid role in increasing the peripheral leukocytes. It generally takes effect at 1 to 3 days after the treatment but with a short duration period. It also has efficacy in treating leukopenia caused by chemotherapy or radiotherapy.
5. It can be used for reducing the vascular permeability and fragility and can be used for the treatment of various kinds of hemorrhage. It also has quick hemostasis effect on menorrhagia, hysterectomy or tonsillectomy.

Uses It belongs to estrogen drug. It can be used for treating leukopenia, various kinds of menopathy, senile vaginitis, and menopausal syndrome. You may also get temporary breast swelling and lumps, menstrual cycle disorders with self-recovery after stopping the drug for about 1 month. Patients of breast hyperplasia, breast lumps, and cancer potentially being related to female hormone-related cancer, aplastic anemia and liver disease patients should be disabled.

Estriol can be a weak or strong estrogen depending on if it is given acutely or chronically when given to immature animals, but is an antagonist when given in combination with estradiol. Estriol may play a role in the development of breast cancer, but based on in vitro research, does appear to act as an antagonist to the G-protein coupled estrogen receptor. Though estriol is used as part of the primarily North American phenomenon of bioidentical hormone replacement therapy, it is not approved for use by the FDAor Health Canada. Though initial research in the 1970s suggested it could be used therapeutically as an estrogen, subsequent research failed to confirm this hypothesis.

Estriol Specification:

Tests Analysis Standard  Results
Description White Or Practically White Crystalline Powder Conform
Identification Infrared Absorption Spectrophotometry
Should conform with CRS
Conform
Clarity of solution The Solution Is Clear And Free From Undissolved Solid Conform
Specific Rotation +54.0°~ +62.0° +57.8°
Loss On Drying ≤0.5% 0.13%
Residue on ignition  ≤0.1% Conform
Relative Materials (Total impurities): ≤ 2.0% Conform
Fineness 10um( 100% Pass ) Conform
Assay 97.0%~102.0% 99.5%
Conclusion (Be Conform With USP30)

—Landmark Elite Team

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